3e64
From Proteopedia
Contents |
Fragment based discovery of JAK-2 inhibitors
Template:ABSTRACT PUBMED 19019674
Disease
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]
About this Structure
3E64 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Fragment-based discovery of JAK-2 inhibitors., Antonysamy S, Hirst G, Park F, Sprengeler P, Stappenbeck F, Steensma R, Wilson M, Wong M, Bioorg Med Chem Lett. 2009 Jan 1;19(1):279-82. Epub 2008 Aug 22. PMID:19019674
Page seeded by OCA on Wed Jan 7 08:48:04 2009
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Antonysamy, S S. | Atp-binding | Chromosomal rearrangement | Disease mutation | Drug discovery | Fragment based | Jak2 | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Proto-oncogene | Sh2 domain | Transferase | Tyrosine-protein kinase
