3c7p

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Template:STRUCTURE 3c7p

Crystal structure of human carbonic anhydrase II in complex with STX237

Template:ABSTRACT PUBMED 18723489

About this Structure

3C7P is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography., Woo LW, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BV, Mol Cancer Ther. 2008 Aug;7(8):2435-44. PMID:18723489

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity., Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV, J Med Chem. 2006 Dec 28;49(26):7683-96. PMID:17181151

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