3f5x

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Template:STRUCTURE 3f5x

CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site

Template:ABSTRACT PUBMED 19097791

About this Structure

3F5X is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Trujillo JI, Kiefer JR, Huang W, Thorarensen A, Xing L, Caspers NL, Day JE, Mathis KJ, Kretzmer KK, Reitz BA, Weinberg RA, Stegeman RA, Wrightstone A, Christine L, Compton R, Li X. 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor. Bioorg Med Chem Lett. 2009 Feb 1;19(3):908-11. Epub 2008 Dec 6. PMID:19097791 doi:10.1016/j.bmcl.2008.11.105

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