3co9
From Proteopedia
Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
Template:ABSTRACT PUBMED 18487044
About this Structure
3CO9 is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.
Reference
- Ruebsam F, Webber SE, Tran MT, Tran CV, Murphy DE, Zhao J, Dragovich PS, Kim SH, Li LS, Zhou Y, Han Q, Kissinger CR, Showalter RE, Lardy M, Shah AM, Tsan M, Patel R, Lebrun LA, Kamran R, Sergeeva MV, Bartkowski DM, Nolan TG, Norris DA, Kirkovsky L. Pyrrolo[1,2-b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3616-21. Epub 2008 May 1. PMID:18487044 doi:10.1016/j.bmcl.2008.04.066
Page seeded by OCA on Wed Feb 11 12:39:47 2009
Categories: RNA-directed RNA polymerase | Viruses | Han, Q. | Kissinger, C R. | Showalter, R E. | Zhao, Q. | Antiviral | Hydrolase | Nucleotide binding | Nucleotide-binding | Nucleotidyltransferase | Protein-ligand complex | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Transcription | Transferase