2hm1

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Image:2hm1.png

Template:STRUCTURE 2hm1

Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor (2)

Template:ABSTRACT PUBMED 17049233

About this Structure

2HM1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Freskos JN, Fobian YM, Benson TE, Moon JB, Bienkowski MJ, Brown DL, Emmons TL, Heintz R, Laborde A, McDonald JJ, Mischke BV, Molyneaux JM, Mullins PB, Bryan Prince D, Paddock DJ, Tomasselli AG, Winterrowd G. Design of potent inhibitors of human beta-secretase. Part 2. Bioorg Med Chem Lett. 2007 Jan 1;17(1):78-81. Epub 2006 Oct 4. PMID:17049233 doi:10.1016/j.bmcl.2006.09.091

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