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2pto

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Image:2pto.png

Template:STRUCTURE 2pto

Mutagenesis of P38 Map Kinase establishes key roles of Phe169 in function and dynamics and reveals a novel DFG-out state

Template:ABSTRACT PUBMED 17441692

About this Structure

2PTO is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bukhtiyarova M, Karpusas M, Northrop K, Namboodiri HV, Springman EB. Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry. 2007 May 15;46(19):5687-96. Epub 2007 Apr 19. PMID:17441692 doi:10.1021/bi0622221

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