2rfx

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Template:STRUCTURE 2rfx

Contents 1 Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF 2 Disease 3 About this Structure 4 Reference

Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF

Template:ABSTRACT PUBMED 18549801

Disease

Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[142830], Spondyloarthropathy, susceptibility to, 1 OMIM:[142830], Stevens-Johnson syndrome, carbamazepine-induced, susceptibility to OMIM:[142830], Hypoproteinemia, hypercatabolic OMIM:[109700]

About this Structure

2RFX is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, Marriott D, Mallal S, Bharadwaj M, Rossjohn J, McCluskey J. Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity. 2008 Jun;28(6):822-32. PMID:18549801 doi:10.1016/j.immuni.2008.04.020

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