2hd1

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Image:2hd1.png

Template:STRUCTURE 2hd1

Contents

Crystal structure of PDE9 in complex with IBMX

Template:ABSTRACT PUBMED 15210993

Disease

Known disease associated with this structure: Epilepsy, pyridoxine-dependent OMIM:[107323]

About this Structure

2HD1 is a 2 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 1tbm. Full crystallographic information is available from OCA.

Reference

  • Huai Q, Wang H, Zhang W, Colman RW, Robinson H, Ke H. Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9624-9. Epub 2004 Jun 21. PMID:15210993 doi:10.1073/pnas.0401120101

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