2b8l

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Image:2b8l.png

Template:STRUCTURE 2b8l

Crystal structure of human beta secretase complexed with inhibitor

Template:ABSTRACT PUBMED 16263281

About this Structure

2B8L is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Stachel SJ, Coburn CA, Steele TG, Crouthamel MC, Pietrak BL, Lai MT, Holloway MK, Munshi SK, Graham SL, Vacca JP. Conformationally biased P3 amide replacements of beta-secretase inhibitors. Bioorg Med Chem Lett. 2006 Feb;16(3):641-4. Epub 2005 Nov 2. PMID:16263281 doi:10.1016/j.bmcl.2005.10.032

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