1az1

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Template:STRUCTURE 1az1

ALRESTATIN BOUND TO C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE

Template:ABSTRACT PUBMED 9405046

About this Structure

1AZ1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Harrison DH, Bohren KM, Petsko GA, Ringe D, Gabbay KH. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant. Biochemistry. 1997 Dec 23;36(51):16134-40. PMID:9405046 doi:10.1021/bi9717136

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