3bes

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Image:3bes.png

Template:STRUCTURE 3bes

Contents

Structure of a Poxvirus ifngbp/ifng Complex

Template:ABSTRACT PUBMED 18252829

Disease

Known disease associated with this structure: AIDS, rapid progression to OMIM:[147570], Aplastic anemia OMIM:[147570], Hepatitis C virus, resistance to OMIM:[147570], TSC2 angiomyolipomas, renal, modifier of OMIM:[147570], Tuberculosis, protection against OMIM:[147570]

About this Structure

3BES is a 2 chains structure of sequences from Ectromelia virus and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nuara AA, Walter LJ, Logsdon NJ, Yoon SI, Jones BC, Schriewer JM, Buller RM, Walter MR. Structure and mechanism of IFN-gamma antagonism by an orthopoxvirus IFN-gamma-binding protein. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1861-6. Epub 2008 Feb 5. PMID:18252829

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