2nqi

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Image:2nqi.png

Template:STRUCTURE 2nqi

Calpain 1 proteolytic core inactivated by WR13(R,R), an epoxysuccinyl-type inhibitor.

Template:ABSTRACT PUBMED 17218315

About this Structure

2NQI is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Cuerrier D, Moldoveanu T, Campbell RL, Kelly J, Yoruk B, Verhelst SH, Greenbaum D, Bogyo M, Davies PL. Development of calpain-specific inactivators by screening of positional scanning epoxide libraries. J Biol Chem. 2007 Mar 30;282(13):9600-11. Epub 2007 Jan 11. PMID:17218315 doi:10.1074/jbc.M610372200

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