3e2u

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Image:3e2u.png

Template:STRUCTURE 3e2u

Contents

Crystal structure of the zink-knuckle 2 domain of human CLIP-170 in complex with CAP-Gly domain of human dynactin-1 (p150-GLUED)

Template:ABSTRACT PUBMED 17828277

Disease

Known disease associated with this structure: Neuropathy, distal hereditary motor, type VIIB OMIM:[601143], Amyotrophic lateral sclerosis, susceptibility to OMIM:[601143]

About this Structure

3E2U is a 8 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 2pzo. Full crystallographic information is available from OCA.

Reference

  • Weisbrich A, Honnappa S, Jaussi R, Okhrimenko O, Frey D, Jelesarov I, Akhmanova A, Steinmetz MO. Structure-function relationship of CAP-Gly domains. Nat Struct Mol Biol. 2007 Oct;14(10):959-67. Epub 2007 Sep 9. PMID:17828277 doi:10.1038/nsmb1291

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