This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2z8c

From Proteopedia

Revision as of 10:08, 16 February 2009 by OCA (Talk | contribs)
Jump to: navigation, search
Image:2z8c.png

Template:STRUCTURE 2z8c

Contents

Phosphorylated insulin receptor tyrosine kinase in complex with (4-{[5-carbamoyl-4-(3-methylanilino)pyrimidin-2-yl]amino}phenyl)acetic acid

Template:ABSTRACT PUBMED 18767165

Disease

Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670], Coronary artery disease, susceptibility to OMIM:[147545], Diabetes mellitus, noninsulin-dependent OMIM:[147545]

About this Structure

2Z8C is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Katayama N, Orita M, Yamaguchi T, Hisamichi H, Kuromitsu S, Kurihara H, Sakashita H, Matsumoto Y, Fujita S, Niimi T. Identification of a key element for hydrogen-bonding patterns between protein kinases and their inhibitors. Proteins. 2008 Sep 2;73(4):795-801. PMID:18767165 doi:10.1002/prot.22207

Page seeded by OCA on Mon Feb 16 12:08:10 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2z8c"
Personal tools