2p8k

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Image:2p8k.png

Template:STRUCTURE 2p8k

Selective screening and design to identify inhibitors of Leishmania major pteridine reductase 1.

Template:ABSTRACT PUBMED 18245389

About this Structure

2P8K is a 8 chains structure of sequences from Leishmania major. Full crystallographic information is available from OCA.

Reference

  • Cavazzuti A, Paglietti G, Hunter WN, Gamarro F, Piras S, Loriga M, Allecca S, Corona P, McLuskey K, Tulloch L, Gibellini F, Ferrari S, Costi MP. Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development. Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1448-53. Epub 2008 Feb 1. PMID:18245389

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