2flm

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Image:2flm.png

Template:STRUCTURE 2flm

Human transthyretin (TTR) complexed with bivalant amyloid inhibitor (6 carbon linker)

Template:ABSTRACT PUBMED 14583036

About this Structure

2FLM is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Green NS, Palaninathan SK, Sacchettini JC, Kelly JW. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization. J Am Chem Soc. 2003 Nov 5;125(44):13404-14. PMID:14583036 doi:10.1021/ja030294z

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