2c5v
From Proteopedia
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
Template:ABSTRACT PUBMED 16492568
About this Structure
2C5V is a 6 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 1oku. Full crystallographic information is available from OCA.
Reference
- Kontopidis G, McInnes C, Pandalaneni SR, McNae I, Gibson D, Mezna M, Thomas M, Wood G, Wang S, Walkinshaw MD, Fischer PM. Differential binding of inhibitors to active and inactive CDK2 provides insights for drug design. Chem Biol. 2006 Feb;13(2):201-11. PMID:16492568 doi:http://dx.doi.org/10.1016/j.chembiol.2005.11.011
Page seeded by OCA on Mon Feb 16 14:03:39 2009
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Fischer, P M. | Gibson, D. | Kontopidis, G. | Mcinnes, C. | Mcnae, I. | Mezna, M. | Pandalaneni, S R. | Thomas, M. | Walkinshaw, M D. | Wang, S. | Wood, G. | Atp-binding | Cell cycle | Cell division | Cycin some | Cyclin | Drug design | Kinase | Ligand exchange | Mitosis | Nucleotide-binding | Phosphorylation | Serine/threonine-protein kinase | Transferase
