2by4

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Template:STRUCTURE 2by4

SR CA(2+)-ATPASE IN THE HNE2 STATE COMPLEXED WITH THE THAPSIGARGIN DERIVATIVE BOC-12ADT.

Template:ABSTRACT PUBMED 16412648

About this Structure

2BY4 is a 1 chain structure of sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Sohoel H, Jensen AM, Moller JV, Nissen P, Denmeade SR, Isaacs JT, Olsen CE, Christensen SB. Natural products as starting materials for development of second-generation SERCA inhibitors targeted towards prostate cancer cells. Bioorg Med Chem. 2006 Apr 15;14(8):2810-5. Epub 2006 Jan 10. PMID:16412648 doi:10.1016/j.bmc.2005.12.001

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