2h79

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Image:2h79.png

Template:STRUCTURE 2h79

Contents

Crystal Structure of human TR alpha bound T3 in orthorhombic space group

Template:ABSTRACT PUBMED 16781732

Disease

Known disease associated with this structure: Pituitary adenoma, nonfunctioning OMIM:[190120]

About this Structure

2H79 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nascimento AS, Dias SM, Nunes FM, Aparicio R, Ambrosio AL, Bleicher L, Figueira AC, Santos MA, de Oliveira Neto M, Fischer H, Togashi M, Craievich AF, Garratt RC, Baxter JD, Webb P, Polikarpov I. Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function. J Mol Biol. 2006 Jul 14;360(3):586-98. Epub 2006 May 19. PMID:16781732 doi:http://dx.doi.org/10.1016/j.jmb.2006.05.008

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