2f8g

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Image:2f8g.png

Template:STRUCTURE 2f8g

HIV-1 protease mutant I50V complexed with inhibitor TMC114

Template:ABSTRACT PUBMED 16480273

About this Structure

2F8G is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Kovalevsky AY, Tie Y, Liu F, Boross PI, Wang YF, Leshchenko S, Ghosh AK, Harrison RW, Weber IT. Effectiveness of nonpeptide clinical inhibitor TMC-114 on HIV-1 protease with highly drug resistant mutations D30N, I50V, and L90M. J Med Chem. 2006 Feb 23;49(4):1379-87. PMID:16480273 doi:http://dx.doi.org/10.1021/jm050943c

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