Template:STRUCTURE 2rh1

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Revision as of 13:22, 16 February 2009 by OCA (Talk | contribs)

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2rh1, resolution 2.40Å ()

Sites:

, , , , , , , , , , , , and

Ligands:

, , , , , , ,

Gene:

ADRB2, ADRB2R, B2AR / E (Homo sapiens, Enterobacteria phage T4)

Domains:

bacteriophage_T4-like_lysozyme, 7tm_1

Structural annotation:
Resources:	InterPro : Ipr000276, Ipr000332, Ipr002233, Ipr017452 Pfam : PF00001 UniProt : P07550

Functional annotation:
Cellular component:	membrane fraction dendrite integral to membrane nucleus axon intracellular part plasma membrane lysosome apical plasma membrane membrane endosome receptor complex sarcolemma integral to plasma membrane
Biological process:	desensitization of G-protein coupled receptor protein signaling pathway by arrestin positive regulation of bone mineralization negative regulation of ossification positive regulation of cell proliferation G-protein signaling, adenylate cyclase activating pathway activation of transmembrane receptor protein tyrosine kinase activity diet induced thermogenesis activation of MAPK activity regulation of sodium ion transport brown fat cell differentiation positive regulation of apoptosis negative regulation of multicellular organism growth G-protein signaling, coupled to cAMP nucleotide second messenger negative regulation of smooth muscle contraction vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure positive regulation of skeletal muscle growth activation of adenylate cyclase activity signal transduction bone resorption protein kinase cascade G-protein coupled receptor protein signaling pathway cell surface receptor linked signal transduction negative regulation of calcium ion transport via voltage-gated calcium channel positive regulation of MAPKKK cascade response to cold receptor-mediated endocytosis regulation of sensory perception of pain positive regulation of vasodilation positive regulation of heart contraction negative regulation of inflammatory response positive regulation of transcription from RNA polymerase II promoter heat generation endosome to lysosome transport
Molecular function:	G-protein coupled receptor activity protein homodimerization activity rhodopsin-like receptor activity norepinephrine binding protein binding drug binding beta-adrenergic receptor activity adrenoceptor activity beta2-adrenergic receptor activity receptor activity signal transducer activity protein complex binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

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