2pwc

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Image:2pwc.png

Template:STRUCTURE 2pwc

HIV-1 protease in complex with a amino decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18348517

About this Structure

2PWC is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s

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