2itq
From Proteopedia
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN G719S MUTATION IN COMPLEX WITH AFN941
Template:ABSTRACT PUBMED 17349580
About this Structure
2ITQ is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 2007 Mar;11(3):217-27. PMID:17349580 doi:http://dx.doi.org/10.1016/j.ccr.2006.12.017
Page seeded by OCA on Mon Feb 16 16:07:02 2009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Boggon, T J. | Eck, M J. | Greulich, H. | Li, Y. | Meyerson, M. | Woo, S. | Yun, C H. | Afn941 | Alternative splicing | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | G719 | Glycoprotein | Membrane | Nucleotide-binding | Phosphorylation | Polymorphism | Receptor | Staurosporine | Transferase | Transmembrane | Tyrosine-protein kinase
