2blc

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Image:2blc.png

Template:STRUCTURE 2blc

SP21 DOUBLE MUTANT P. VIVAX DIHYDROFOLATE REDUCTASE IN COMPLEX WITH DES-CHLOROPYRIMETHAMINE

Template:ABSTRACT PUBMED 16135570

About this Structure

2BLC is a 1 chain structure of sequence from Plasmodium vivax. Full crystallographic information is available from OCA.

Reference

  • Kongsaeree P, Khongsuk P, Leartsakulpanich U, Chitnumsub P, Tarnchompoo B, Walkinshaw MD, Yuthavong Y. Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resistance. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13046-51. Epub 2005 Aug 31. PMID:16135570

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