1tu6

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Image:1tu6.png

Template:STRUCTURE 1tu6

Cathepsin K complexed with a ketoamide inhibitor

Template:ABSTRACT PUBMED 15341947

About this Structure

1TU6 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL. Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4897-902. PMID:15341947 doi:10.1016/j.bmcl.2004.07.031

Page seeded by OCA on Mon Feb 16 16:21:34 2009

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