1tlc

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Image:1tlc.png

Template:STRUCTURE 1tlc

THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89

Template:ABSTRACT PUBMED 7724588

About this Structure

1TLC is a 2 chains structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Weichsel A, Montfort WR, Ciesla J, Maley F. Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3493-7. PMID:7724588

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