1t3r

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Template:STRUCTURE 1t3r

HIV protease wild-type in complex with TMC114 inhibitor

Template:ABSTRACT PUBMED 15771427

About this Structure

1T3R is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p

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