2hhh

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Image:2hhh.png

Template:STRUCTURE 2hhh

Crystal structure of kasugamycin bound to the 30S ribosomal subunit

Template:ABSTRACT PUBMED 16998488

About this Structure

2HHH is a 21 chains structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

  • Schluenzen F, Takemoto C, Wilson DN, Kaminishi T, Harms JM, Hanawa-Suetsugu K, Szaflarski W, Kawazoe M, Shirouzu M, Nierhaus KH, Yokoyama S, Fucini P. The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat Struct Mol Biol. 2006 Oct;13(10):871-8. Epub 2006 Sep 24. PMID:16998488 doi:10.1038/nsmb1145

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