2rg3

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Image:2rg3.png

Template:STRUCTURE 2rg3

Contents

Covalent complex structure of elastase

Template:ABSTRACT PUBMED 18318470

Disease

Known disease associated with this structure: Hematopoiesis, cyclic OMIM:[130130], Neutropenia, congenital OMIM:[130130]

About this Structure

2RG3 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Huang W, Yamamoto Y, Li Y, Dou D, Alliston KR, Hanzlik RP, Williams TD, Groutas WC. X-ray snapshot of the mechanism of inactivation of human neutrophil elastase by 1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives. J Med Chem. 2008 Apr 10;51(7):2003-8. Epub 2008 Mar 5. PMID:18318470 doi:10.1021/jm700966p

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