2gpl

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Image:2gpl.png

Template:STRUCTURE 2gpl

TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors

Template:ABSTRACT PUBMED 16793518

About this Structure

2GPL is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Groll M, Gotz M, Kaiser M, Weyher E, Moroder L. TMC-95-based inhibitor design provides evidence for the catalytic versatility of the proteasome. Chem Biol. 2006 Jun;13(6):607-14. PMID:16793518 doi:10.1016/j.chembiol.2006.04.005

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