1ohz
From Proteopedia
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COHESIN-DOCKERIN COMPLEX FROM THE CELLULOSOME OF CLOSTRIDIUM THERMOCELLUM
Overview
The utilization of organized supramolecular assemblies to exploit the, synergistic interactions afforded by close proximity, both for enzymatic, synthesis and for the degradation of recalcitrant substrates, is an, emerging theme in cellular biology. Anaerobic bacteria harness a, multiprotein complex, termed the "cellulosome," for efficient degradation, of the plant cell wall. This megadalton catalytic machine organizes an, enzymatic consortium on a multifaceted molecular scaffold whose "cohesin", domains interact with corresponding "dockerin" domains of the enzymes., Here we report the structure of the cohesin-dockerin complex from, Clostridium thermocellum at 2.2-A resolution. The data show that the, beta-sheet cohesin domain interacts predominantly with one of the helices, of the ... [(full description)]
About this Structure
1OHZ is a [Protein complex] structure of sequences from [Clostridium thermocellum] with NO3, CA, CL and EDO as [ligands]. Active as [[1]], with EC number [3.2.1.8]. Full crystallographic information is available from [OCA].
Reference
Cellulosome assembly revealed by the crystal structure of the cohesin-dockerin complex., Carvalho AL, Dias FM, Prates JA, Nagy T, Gilbert HJ, Davies GJ, Ferreira LM, Romao MJ, Fontes CM, Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13809-14. Epub 2003 Nov 17. PMID:14623971
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