1q2p

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Image:1q2p.png

Template:STRUCTURE 1q2p

SHV-1 class A beta-lactamase complexed with penem WAY185229

Template:ABSTRACT PUBMED 15588091

About this Structure

1Q2P is a 1 chain structure of sequence from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

Reference

  • Venkatesan AM, Gu Y, Dos Santos O, Abe T, Agarwal A, Yang Y, Petersen PJ, Weiss WJ, Mansour TS, Nukaga M, Hujer AM, Bonomo RA, Knox JR. Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates. J Med Chem. 2004 Dec 16;47(26):6556-68. PMID:15588091 doi:10.1021/jm049680x

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