1zxc

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Image:1zxc.png

Template:STRUCTURE 1zxc

Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor

Template:ABSTRACT PUBMED 16084720

About this Structure

1ZXC is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Levin JI, Chen JM, Laakso LM, Du M, Du X, Venkatesan AM, Sandanayaka V, Zask A, Xu J, Xu W, Zhang Y, Skotnicki JS. Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4345-9. PMID:16084720 doi:http://dx.doi.org/10.1016/j.bmcl.2005.06.072

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