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2b2x

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Image:2b2x.png

Template:STRUCTURE 2b2x

VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab

Template:ABSTRACT PUBMED 16597831

About this Structure

2B2X is a 6 chains structure of sequences from Mus musculus and Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Clark LA, Boriack-Sjodin PA, Eldredge J, Fitch C, Friedman B, Hanf KJ, Jarpe M, Liparoto SF, Li Y, Lugovskoy A, Miller S, Rushe M, Sherman W, Simon K, Van Vlijmen H. Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design. Protein Sci. 2006 May;15(5):949-60. Epub 2006 Apr 5. PMID:16597831 doi:10.1110/ps.052030506

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