2hs2

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Image:2hs2.png

Template:STRUCTURE 2hs2

Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)

Template:ABSTRACT PUBMED 16962136

About this Structure

2HS2 is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

Kovalevsky AY, Liu F, Leshchenko S, Ghosh AK, Louis JM, Harrison RW, Weber IT. Ultra-high resolution crystal structure of HIV-1 protease mutant reveals two binding sites for clinical inhibitor TMC114. J Mol Biol. 2006 Oct 13;363(1):161-73. Epub 2006 Aug 4. PMID:16962136 doi:10.1016/j.jmb.2006.08.007

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Categories: Human immunodeficiency virus 1 | Kovalevsky, A Y. | Liu, F. | Weber, I T. | Aspartic protease active site surface binding site

2hs2

From Proteopedia

Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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