1xqc

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Image:1xqc.png

Template:STRUCTURE 1xqc

X-ray structure of ERalpha LBD bound to a tetrahydroisoquinoline SERM ligand at 2.05A resolution

Template:ABSTRACT PUBMED 15658851

About this Structure

1XQC is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Geiser M, Halleux C, Kallen J, Keller H, Ramage P. Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands. J Med Chem. 2005 Jan 27;48(2):364-79. PMID:15658851 doi:10.1021/jm040858p

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