2rn5

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Image:2rn5.png

Template:STRUCTURE 2rn5

Contents

Humal Insulin Mutant B31Lys-B32Arg

Template:ABSTRACT PUBMED 18491415

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2RN5 is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Bocian W, Borowicz P, Mikolajczyk J, Sitkowski J, Tarnowska A, Bednarek E, Glabski T, Tejchman-Malecka B, Bogiel M, Kozerski L. NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer. Biopolymers. 2008 Oct;89(10):820-30. PMID:18491415 doi:10.1002/bip.21018

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