2h42

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Image:2h42.png

Template:STRUCTURE 2h42

Crystal structure of PDE5 in complex with sildenafil

Template:ABSTRACT PUBMED 16735511

About this Structure

2H42 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang H, Liu Y, Huai Q, Cai J, Zoraghi R, Francis SH, Corbin JD, Robinson H, Xin Z, Lin G, Ke H. Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development. J Biol Chem. 2006 Jul 28;281(30):21469-79. Epub 2006 May 30. PMID:16735511 doi:10.1074/jbc.M512527200

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