1tb6

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Image:1tb6.png

Template:STRUCTURE 1tb6

Contents

2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex

Template:ABSTRACT PUBMED 15311269

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

1TB6 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Li W, Johnson DJ, Esmon CT, Huntington JA. Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat Struct Mol Biol. 2004 Sep;11(9):857-62. Epub 2004 Aug 15. PMID:15311269 doi:10.1038/nsmb811

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