2vx0
From Proteopedia
EPHB4 KINASE DOMAIN INHIBITOR COMPLEX
Template:ABSTRACT PUBMED 18434142
About this Structure
2VX0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ. Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines. Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142 doi:10.1016/j.bmcl.2008.04.015
Page seeded by OCA on Mon Feb 16 23:56:58 2009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Barratt, D. | Brassington, C A. | Green, I. | Kettle, J G. | Leach, A G. | Mccall, E J. | Read, J. | Valentine, A L. | Atp-binding | Glycoprotein | Kinase | Membrane | Mutant | Nucleotide-binding | Phosphoprotein | Polymorphism | Receptor | Receptor tyrosine kinase | Transferase | Transmembrane | Tyrosine-protein kinase | Unphosphorylated