2ax1

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Image:2ax1.png

Template:STRUCTURE 2ax1

Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5ee)

Template:ABSTRACT PUBMED 16451069

About this Structure

2AX1 is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Powers JP, Piper DE, Li Y, Mayorga V, Anzola J, Chen JM, Jaen JC, Lee G, Liu J, Peterson MG, Tonn GR, Ye Q, Walker NP, Wang Z. SAR and mode of action of novel non-nucleoside inhibitors of hepatitis C NS5b RNA polymerase. J Med Chem. 2006 Feb 9;49(3):1034-46. PMID:16451069 doi:10.1021/jm050859x

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