2cig

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Image:2cig.png

Template:STRUCTURE 2cig

DIHYDROFOLATE REDUCTASE FROM MYCOBACTERIUM TUBERCULOSIS INHIBITED BY THE ACYCLIC 4R ISOMER OF INH-NADP A DERIVATIVE OF THE PRODRUG ISONIAZID.

Template:ABSTRACT PUBMED 16648861

About this Structure

2CIG is a 1 chain structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Argyrou A, Vetting MW, Aladegbami B, Blanchard JS. Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid. Nat Struct Mol Biol. 2006 May;13(5):408-13. Epub 2006 Apr 30. PMID:16648861 doi:10.1038/nsmb1089

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