This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2itx
From Proteopedia
CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH AMP-PNP
Template:ABSTRACT PUBMED 17349580
About this Structure
2ITX is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yun CH, Boggon TJ, Li Y, Woo MS, Greulich H, Meyerson M, Eck MJ. Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity. Cancer Cell. 2007 Mar;11(3):217-27. PMID:17349580 doi:http://dx.doi.org/10.1016/j.ccr.2006.12.017
Page seeded by OCA on Tue Feb 17 01:02:57 2009
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Boggon, T J. | Eck, M J. | Greulich, H. | Li, Y. | Meyerson, M. | Woo, S. | Yun, C H. | Alternative splicing | Amp-pnp | Anp | Anti-oncogene | Atp-binding | Cell cycle | Disease mutation | Egfr | Epidermal growth factor | Glycoprotein | Kinase | Membrane | Nucleotide-binding | Phosphorylation | Polymorphism | Receptor | Transferase | Transmembrane | Tyrosine-protein kinase
