2zdt

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Image:2zdt.png

Template:STRUCTURE 2zdt

Crystal Structure of human JNK3 complexed with an isoquinolone inhibitor

Template:ABSTRACT PUBMED 18313930

About this Structure

2ZDT is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Asano Y, Kitamura S, Ohra T, Itoh F, Kajino M, Tamura T, Kaneko M, Ikeda S, Igata H, Kawamoto T, Sogabe S, Matsumoto S, Tanaka T, Yamaguchi M, Kimura H, Fukumoto S. Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2). Bioorg Med Chem. 2008 Apr 15;16(8):4699-714. Epub 2008 Feb 13. PMID:18313930 doi:10.1016/j.bmc.2008.02.028

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