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2g27
From Proteopedia
Contents |
Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring
Template:ABSTRACT PUBMED 16480874
Disease
Known disease associated with this structure: Renal tubular dysgenesis OMIM:[179820], Hyperproreninemia OMIM:[179820]
About this Structure
2G27 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Holsworth DD, Cai C, Cheng XM, Cody WL, Downing DM, Erasga N, Lee C, Powell NA, Edmunds JJ, Stier M, Jalaie M, Zhang E, McConnell P, Ryan MJ, Bryant J, Li T, Kasani A, Hall E, Subedi R, Rahim M, Maiti S. Ketopiperazine-based renin inhibitors: optimization of the "C" ring. Bioorg Med Chem Lett. 2006 May 1;16(9):2500-4. Epub 2006 Feb 15. PMID:16480874 doi:http://dx.doi.org/10.1016/j.bmcl.2006.01.084
Page seeded by OCA on Tue Feb 17 02:04:29 2009
