2pl0

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Image:2pl0.png

Template:STRUCTURE 2pl0

Contents

LCK bound to imatinib

Template:ABSTRACT PUBMED 17910071

Disease

Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]

About this Structure

2PL0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Jacobs MD, Caron PR, Hare BJ. Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex. Proteins. 2007 Oct 1;70(4):1451-1460. PMID:17910071 doi:10.1002/prot.21633

Page seeded by OCA on Tue Feb 17 02:23:36 2009

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