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2fky
From Proteopedia
crystal structure of KSP in complex with inhibitor 13
Template:ABSTRACT PUBMED 16439123
About this Structure
2FKY is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fraley ME, Garbaccio RM, Arrington KL, Hoffman WF, Tasber ES, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Fernandes C, Schaber MD, Lobell RB, Tao W, South VJ, Yan Y, Kuo LC, Prueksaritanont T, Shu C, Torrent M, Heimbrook DC, Kohl NE, Huber HE, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 2: the design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1775-9. Epub 2006 Jan 24. PMID:16439123 doi:10.1016/j.bmcl.2006.01.030
Page seeded by OCA on Tue Feb 17 02:41:17 2009
