1vsn

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Image:1vsn.png

Template:STRUCTURE 1vsn

Crystal structure of a potent small molecule inhibitor bound to cathepsin K

Template:ABSTRACT PUBMED 16413777

About this Structure

1VSN is a 1 chain structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2fdz. Full crystallographic information is available from OCA.

Reference

  • Li CS, Deschenes D, Desmarais S, Falgueyret JP, Gauthier JY, Kimmel DB, Leger S, Masse F, McGrath ME, McKay DJ, Percival MD, Riendeau D, Rodan SB, Therien M, Truong VL, Wesolowski G, Zamboni R, Black WC. Identification of a potent and selective non-basic cathepsin K inhibitor. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1985-9. Epub 2006 Jan 18. PMID:16413777 doi:10.1016/j.bmcl.2005.12.071

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