2qic

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Image:2qic.png

Template:STRUCTURE 2qic

Contents

Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide

Template:ABSTRACT PUBMED 18533182

Disease

Known disease associated with this structure: Squamous cell carcinoma, head and neck OMIM:[601566]

About this Structure

2QIC is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pena PV, Hom RA, Hung T, Lin H, Kuo AJ, Wong RP, Subach OM, Champagne KS, Zhao R, Verkhusha VV, Li G, Gozani O, Kutateladze TG. Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. J Mol Biol. 2008 Jul 4;380(2):303-12. Epub 2008 May 2. PMID:18533182 doi:10.1016/j.jmb.2008.04.061

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