2ayp

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Image:2ayp.png

Template:STRUCTURE 2ayp

Crystal Structure of CHK1 with an Indol Inhibitor

Template:ABSTRACT PUBMED 16242328

About this Structure

2AYP is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lin NH, Xia P, Kovar P, Park C, Chen Z, Zhang H, Rosenberg SH, Sham HL. Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors. Bioorg Med Chem Lett. 2006 Jan 15;16(2):421-6. Epub 2005 Oct 18. PMID:16242328 doi:10.1016/j.bmcl.2005.09.064

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